Cis(gender)- is defined as the sex you are assigned at birth, while transgender is an umbrella term for people whose gender identity differs from the sex they are assigned at birth. Recently I have been working on preparation of various keynote presentations on paradigm shift for gerontology specifically on anti-aging. Seems gerontologists to add life to your years and years to your life have shifted from pursing life extension strategies to anti-aging. In that regard I have Google-searched for biological markers for aging. One of the tests I have found relates to the significant loss of hormone levels- more specifically DHEA.-According to Roy Walford in his textbook ( The 120 year diet ) table 2.2 in males DHEA declines from 3400 ng./ml of plasma in the 20-30 age group to less than 900 ng/ml by age 60. Corresponding figures for females are 2200 to 800 .
The Fifth edition (2013) of Disease Prevention and Treatment published by Life Extension Foundation on p. 608 details how DHEA is converted to Androstenediol an intermediate hormone which can then produce either and/or both– the male and female sex hormones, viz. testosterone and the 3 major estrogens (estrone,, estradiol and estriol). The hormonal cascade also shows that the enzyme aromatase can convert testosterone to the female sex hormones.
I wonder if an imbalance of this hormonal cascade can produce the transgenders we are witnessing. Maybe by altering these conversions we could preventive the transgender phenomenon.